Our book, World of Vaccinology 2024, is a multidisciplinary scientific initiative dedicated to understanding the evolving cellular and molecular biology of vaccines within bio- and regenerative medicine. The book’s primary focus is to explain its relevance to vaccinology and immunotherapy. Summarize the vaccine development and immunotherapy advancements discussed in the book, including new therapeutic strategies and technological innovations. Recent breakthroughs in vaccination have illuminated the therapeutic applications of vaccines for a broader array of cancers and immunologically mediated, noncommunicable diseases (NCDs), revealing new possibilities in disease prevention and treatment. The book reviews the evolution of immunotherapies from early bacterial approaches like Bacillus Calmette–Guérin (BCG) therapy for bladder cancer to modern prophylactic and therapeutic vaccines. Building on the success of mRNA vaccines for infectious diseases, this book explores their potential in cancer nanomedicine and highlights recent immunotherapy advances and their prospects. Section 2 on “Immunotherapies: Preventive and Therapeutic Advancements”, (Chapters 9 through 13), explores cancer vaccines and other NCDs and disorders. Some types of immunotherapies only target certain cells of the immune system. Others can disturb the immune system in a general way by therapeutic monoclonal antibodies (mAbs), and immune checkpoint inhibitors, oncolytic virus therapy including cancer vaccines, and T-cell transfer therapies. These points provide a comprehensive overview of the dynamic field of immunotherapy, setting the stage for detailed discussions throughout the book. Highlight the book's unique aspects, such as multidisciplinary approaches, the latest research findings, or case studies. The book is intended for immunologists, researchers, clinicians, and students. It aims to serve its readers by providing new insights, techniques, and frameworks for understanding complex immunological interactions. The authors anticipate that this book will contribute to the education and advancement of its readers, detailing included resources like case studies, diagrams, and interactive content. We aim to elevate role models in this field and underscore the benefits of these advancements to human health and scientific innovation. World of Vaccinology 2024 is not just a product of one individual’s work but a testament to the principles of collaboration and teamwork. It encourages contributions from experts across various disciplines, both nationally and internationally.