This is a complete, rich and valuable resource of knowledge on tuberculosis. It is the first of its kind, a thoroughly updated edition, aligning according to the latest Programmatic Management of Drug-resistant Tuberculosis (PMDT) Guidelines. Several authors from various interdisciplinary specialities, with vast experience in their domain, contributed to the multidisciplinary approach towards tuberculosis. This book opens with a comprehensive content page which is subdivided into 6 sections. Each section is unique as it covers different aspects of tuberculosis like introduction, laboratory diagnosis, clinical features, management and prevention. Special stress has been laid on the inclusion of new topics like science of TB vaccine, laboratory diagnosis and treatment of drug resistant TB, Nanotechnology in TB and National Tuberculosis Elimination Program (NTEP) and how it evolved from Revised National Tuberculosis Program. Of note, the detailed explanation of molecular tests in the diagnosis of tuberculosis, with special attention on DNA polymerase chain reaction (PCR) testing was addressed. Currently, PCR technique is the cornerstone for cartridge based nucleic acid amplification test (CBNAAT), the most widely used point of care diagnostic test in the world. In addition, the evolution of COVID-19 pandemic situation and its effect on TB in India is beautifully covered. On the other hand, chapters specifically focussing on extra pulmonary tuberculosis and its management have been clearly illustrated from a holistic viewpoint for the accurate understanding and application of the reader. Primarily this book aims to give the readers an easy understanding of a complex disease and to serve them to adequately apply the concepts while dealing with TB cases. In addition, this book also serves to enrich the knowledge of undergraduate and postgraduate students in tackling complicated practical questions.