This Volume of Progress in Clinical Neurosciences brings to you a synthesized overview of clinically relevant topics in an easy-to-read format. It would enable both the practicing Clinician and the student in training to update their knowledge and apply it in day-to-day practice. The most significant advances in traumatic brain injury, pituitary adenomas, myasthenia gravis, epilepsy source localization, and poststroke rehabilitation have been addressed. The controversies regarding the management of low grade gliomas, solitary brain metastasis and optimal surgical approach to colloid cysts are discussed cogently. A systematic diagnostic approach to myelopathy and encephalopathy is illustrated. The future of neurosurgical education is simulation and there is a detailed explanation of this strategy. The importance and relevance of clinical examination in today's era of highly advanced diagnostic imaging cannot be understated and this has been put forth emphatically. Finally there is a discussion on how to inspire hope while breaking bad news to the patient and family just to uncover a silver lining in the darkest of clouds.//Dr. V. P. Singh is involved in neurosurgical education having being a faculty at All India Institute of Medical Sciences, New Delhi, for everal years. He is actively involved in several subspecialty neurosurgical societies dealing with cerebrovascular surgery, pediatric neurosurgery, and stereotactic and functional neurosurgery. He is the CME convenor of the Neurological Society of India and the editor of Journal of Pediatric Neurosciences. Currently he is a senior consultant at Indraprastha Apollo Hospital, New Delhi.//Dr. Muralidharan Nair is the professor and head of Department of Neurology at the Sree Chitra Tirunal Institute of Medical Sciences and Technology, Thiruvananthapuram, Kerala, and has 28 years of clinical and teaching experience. He has an interest in biomedical ethics and history of neurology and runs a history of neurology session for postgraduates. He specializes in the diagnosis and management of neuromuscular disorders, particularly myasthenia gravis, muscular dystrophies, and multiple sclerosis. He was nominated for the Dr. Abdul Gafoor oration this year by the NSI Kerala Chapter.//An award-winning international medical and scientific publisher, Thieme has demonstrated its commitment to the highest standard of quality in the state-ofthe-art content and presentation of all of its products. Thieme's trademark blue and silver covers have become synonymous with excellence in publishing.