The current edition of the book has been thoroughly revised keeping in mind to be used as a handbook containing essential features required for management of patients with rheumatic diseases. The manual is intended for use by residents and consultants in internists, pediatricians and rheumatologists and orthopedicsurgeons. Written by rheumatologists, radiologists from India and abroad of national and international repute.Salient features of the manual˜… Inclusions of flowcharts, diagrams and tables substituting descriptive texts.˜… 12 sections on all aspects of assessment of rheumatic diseases, including history taking approach, examinations, drugs, lab investigations, image investigations and all rheumatic diseases.˜… A chapter on techniques in biomarker detection, interpretations of ANA pattern and HLA added.˜… Musculoskeletal ultrasound deals with extensively including probe positioning, tissue characteristics, upper and lower limb ultrasonography abnormalities. A new chapter on US guided injections has been added.˜… Practical aspects including diagnosis, investigational abnormalities of all rheumatic diseases have been dealt individually highlighting the key points.