This textbook includes 70 chapters contributed by an exceptional group of experts in all areas of hepato-pancreato-biliary diseases, bringing a multi-disciplinary approach to treatments. The book is designed to cover all aspects of the liver and pancreatic anatomy and pathology, as well as therapy. The topics are comprehensively reviewed, and as well as summarizing the previous works, the authors provide discussions of practice-changing techniques and approaches to therapy of HBP cancers. Treating the diseases in hepato-pancreato-biliary regions is particularly difficult due to the complex anatomy, aggressive biological behavior, and poor prognosis. Therefore, ample illustrations are included to tackle these challenges.The IASGO Textbook of Multi-Disciplinary Management of Hepato-Pancreato-Biliary Diseases aims to update the academic and non-academic medical professionals, such as surgeons, radiation oncologists, medical oncologists, gastroenterologists, interventional radiologists, radiologists, basic scientists. In collaboration with the International Association of Surgeons, Gastroenterologists and Oncologists (IASGO), delivers a valuable and well-organized textbook for medical professionals.