This handbook highlights the relevance of the social sciences in global public health and their significantly crucial role in the explanation of health and illness in different population groups, the improvement of health, and the prevention of illnesses around the world. Knowledge generated via social science theories and research methodologies allows healthcare providers, policy-makers, and politicians to understand and appreciate the lived experience of their people, and to provide sensitive health and social care to them at a time of most need.  Social sciences, such as medical sociology, medical anthropology, social psychology, and public health are the disciplines that examine the sociocultural causes and consequences of health and illness. It is evident that biomedicine cannot be the only answer to improving the health of people. What makes social sciences important in global public health is the critical role social, cultural, economic, and political factors play in determining or influencing the health of individuals, communities, and the larger society and nation. This handbook is comprehensive in its nature and contents, which range from a more disciplinary-based approach and theoretical and methodological frameworks to different aspects of global public health. It covers Discussions of the social science disciplines and their essence, concepts, and theories relating to global public healthTheoretical frameworks in social sciences that can be used to explain health and illness in populations Methodological inquiries that social science researchers can use to examine global public health issues and understand social issues relating to health in different population groups and regionsExamples of social science research in global public health areas and concerns as well as population groupsThe Handbook of Social Sciences and Global Public Health is a useful reference for students, researchers, lecturers, practitioners, and policymakers in global health, public health, and social science disciplines; and libraries in universities and health and social care institutions. It offers readers a good understanding of the issues that can impact the health and well-being of people in society, which may lead to culturally sensitive health and social care for people that ultimately will lead to a more equitable society worldwide.