This 3rd edition has been thoroughly revised and updated with inclusion of MCQs at the end of every chapter, which is a must to refresh the knowledge of the students. Those who are planning to establish a blood bank or are already in this business shall find the guidelines in the chapter on standards of blood bank, incorporated from NACO, which is a boon for them. The dedicated chapters of Obstetrics and Gynecology and Pediatrics are an asset to the residents as it has been observed that the residents of these specialties find it very challenging to advise the proper blood product to their patients. For the UG and PG students of Pathology, the blood banking is almost a neglected subject, completely overshadowed by Histopathology, Cytology, and Hematology. This edition shall definitely enhance the knowledge of theory and practical of blood banking of these students. The technicians are the backbone of the blood bank. They must be updated with the latest equipment and techniques. They pick up their knowledge and skill of the subject during their teaching and training of DMLT and BMLT. Their theory and practical examination in blood banking are more comprehensive and exhaustive than the students of MBBS. The book is designed keeping in mind the students of these technical courses as well. The other advantage is that the book is very handy and can be used as a manual of blood banking and transfusion medicine.