The National Medical Council of India (NMC) has revised the syllabus for the bachelor’s degree program in medicine. In this edition, new topics relevant in the current scenario have been included and many outdated topics have been removed.///Key Features Keeping with the previous competency-based medical education (CBME) based content, all chapters have been revised and content has been reorganized into thirty chapters to meet the needs of the student as per competency-based curriculum. Each chapter opens with the competency and specific learning objectives as per the guidelines provided by NMC and various universities. The learning objectives for every chapter have been thoroughly revised and updated the text to ensure that all competencies and learning objectives are clearly addressed in a logical order. Revised self-assessment questions in the form of structured long essay questions (SLEQs), short essay questions (SEQs), short answer questions (SAQs), case vignette-based questions (CVBQs) and multiple choice questions (MCQs), have been provided at the end of each chapter to give an idea of the type of questions that are put across in the examination for various universities. Several universities and medical colleges in India have recommended this CBME-based book in their curriculum for Indian medical graduate.